Oud saafi ah Saliid udgoon oo calaamad u ah shumaca iyo saabuunta samaynta jumlo diffuser saliid lagama maarmaan ah oo cusub

Oud saafi ah Saliid udgoon udgoon oo loogu talagalay shumaca iyo saabuunta samaynta jumlo diffuser saliid lagama maarmaan ah oo cusub oo loogu talagalay fidiyayaasha gubta cawsduur

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Halabuurka kiimikada ee ATR

Halabuurka kiimikaad ee ATR inta badan waa qaybo isbedeli karo iyo qaybo aan kacsanayn. Saliidda muhiimka ah ee ATR (ATEO) waxaa loo tixgeliyaa inay tahay qaybta firfircoon ee ATR, iyo waxa ku jira ATEO waa tilmaanta kaliya ee go'aaminta nuxurka ATR. Waqtigan xaadirka ah, waxaa jira cilmi-baarisyo kala duwan oo ku saabsan qaybo isbeddelaya iyo cilmi-baaris yar oo lagu sameeyay qaybaha aan isbeddelin. Qaybaha isbedbeddelaya waa kuwo aad u adag, iyo noocyada ugu muhiimsan ee dhismaha waa phenylpropanoids (phenylpropanoids fudud, lignans iyo coumarins) iyo terpenoids (monoterpenes, sesquiterpenes, diterpenoids iyo triterpenes). Qaybaha aan isbeddelayn ayaa u badan alkaloids, aldehydes iyo acids, quinones iyo ketones, sterols, amino acids, iyo carbohydrates. Natiijooyinka daraasadda ka kooban kiimikada ATR waxay gacan ka geysan doontaa horumarinta cilmi-baaristeeda tayada.

Halabuurka kacsan

Cilmi-baarayaashu waxay isticmaaleen farsamooyinka baaritaanka falanqaynta sida chromatography iyo GC-MS si ay u falanqeeyaan qaybaha kiimikada ee ATR asal ahaan kala duwan, noocyo kala duwan, hababka kala duwan ee soo saarista iyo qaybo kala duwan. Daraasado hore ayaa tilmaamay in walxaha kiimikada ee ugu muhiimsan ee ATR ay yihiin saliid aan isbeddelin, kuwaas oo ah tilmaamayaasha muhiimka ah ee qiimeynta tayada ATR. α-Asarone iyo β-asarone waxay ku xisaabtameen 95% saliidaha ATR ee kacsan waxaana loo aqoonsaday inay yihiin qaybo sifo ah (Sawirka 1) (Lam iyo al., 2016). "Pharmacopoeia ee Jamhuuriyadda Dadka Shiinaha" (Daabacaada 2020) waxay diiwaan gelisaa in saliidda kacsan ee ATR aysan ka yarayn 1.0% (ml/g). Waqtigan xaadirka ah, noocyo badan oo qaybo saliid ah ayaa laga helay ATR

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Acori TatarinowiiRhizoma (ATR,Shi Chang PuChinese) waa rizome engegan eeAcorus tatarinowiiSchott., Geedo sannadle ah oo ka mid ah Araceae Juss (Yan et al., 2020b). Waxa marka hore lagu diiwaan geliyey shaqooyinka caadiga ah ee dawo-dhaqameedka Shiinaha "Shen Nong's Materia Medica," waxaana lagu taxay heerka ugu sarreeya. Saamaynta ATR waxay u badan tahay inay dib u soo nooleeyaan, dejiyaan maskaxda, xaliyaanshi(qoyaanka) oo is waafajiway(caloosha) (Lam iyo al., 2016b). Kiliinik ahaan, ATR waxaa si weyn loogu isticmaalaa xanuunada dareemayaasha, nidaamka wadnaha, habka dheefshiidka caloosha iyo mindhicirka, habka neefsashada ee Shiinaha (Lam iyo al., 2016b;Li iyo al., 2018aiyo daawaynta suuxdinta, niyad-jabka, amnesia, miyir-qabka, walaaca, hurdo la'aanta, aphasia, tinnitus, kansarka, waallida, faaliga, cudurrada maqaarka, iyo cudurrada kale ee kakan (Lee iyo al., 2004;Liu iyo al., 2013;Lam iyo al., 2019;Li J. iyo al., 2021). Sanadihii la soo dhaafay, cilmi-baaristeeda dawooyinka ayaa muujisay in ATR ay leedahay saameyno kala duwan oo dawooyin ah, oo ay ku jiraan anti-epileptic, sedative, hypnotic, anti-convulsant, anti-tussive, anti-asthmatic, anti-oxidant, anti-buro iyo wixii la mid ah (Wu iyo al., 2015;Lam iyo al., 2017;Fu iyo al., 2020;Shi iyo al., 2020;Zhang W. iyo al., 2022). Daraasadihii hore waxay muujiyeen in ATR ay u ballanqaadayso musharraxa daroogada ee suurtogalka ah ee daaweynta cudurka Alzheimers (AD), niyad-jabka, ama colitis. Marka la eego waxtarka saxda ah ee bukaan-socodka ee ATR iyo helitaanka joogtada ah ee waxqabadyada dawooyinka cusub iyo maaddooyinka firfircoon, waxay si weyn uga welwelsan tahay adduunka oo dhan sannadihii la soo dhaafay waxayna noqotay mid ka mid ah noocyada daawada Shiinaha ee kulul ee cilmi-baarista ee caafimaadka.

Halabuurka kiimikada iyo saamaynta dawooyinka ee ATR ayaa si aad ah loo soo sheegay dhowrkii sano ee la soo dhaafay, iyo farmashiyeheeda iyo sunteeda ayaa sidoo kale lagu bartay heerar kala duwan. Si kastaba ha ahaatee, inta badan warbixinadii hore waa kala firirsan yihiin, oo aan lahayn soo koobid nidaamsan iyo soo bandhigista ATR. Sidaa darteed, dib u eegistani waxay ujeedadeedu tahay inay bixiso soo koobid dhamaystiran iyo dood ku saabsan ka kooban kiimikada, farmashiistaha, farmasokinetics iyo sifooyinka sunta, taas oo gacan ka geysata dhaqanka caafimaad ee dheeraadka ah iyo codsiga ATR.