100% Saliida Dabiiciga ah ee Eucommiae Foliuml Saliida Muhiimka ah ee Daryeelka Maqaarka

100% Saliida Dabiiciga ah ee Dabiiciga ah ee Eucommiae Foliuml Saliida Muhiimka ah ee Daryeelka Maqaarka Sawirka

sharaxaad gaaban:

Eucommia ulmoides(EU) (oo inta badan loo yaqaan "Du Zhong" ee luqadda Shiinaha) waxay ka tirsan yihiin qoyska Eucommiaceae, oo ah geed yar oo u dhashay Bartamaha Shiinaha.1]. Geedkan waxaa si ballaaran loogu beeraa Shiinaha si baaxad leh, sababtoo ah muhiimadda daawada. Qiyaastii 112 xeryood ayaa laga soocay EU kuwaas oo ay ku jiraan lignans, iridoids, phenolics, steroids, iyo xeryahooda kale. Caanaha geedo dheellitiran ee geedkan (sida shaaha macaan) ayaa muujiyay qaar ka mid ah sifooyinka daawooyinka. Caleenta EU waxay leedahay hawlo sare oo la xidhiidha kortex, ubax, iyo miro [2,3]. Caleemaha EU ayaa la sheegay inay kor u qaadaan xoogga lafaha iyo murqaha jirka [4], taaso keenta cimri dheer iyo kor u qaadida bacriminta aadanaha [5]. Caanaha shaaha macaan ee laga sameeyay caleenta Midowga Yurub ayaa lagu soo warramey inay yareyso dufanka ayna xoojiso dheef-shiid kiimikaadka tamarta. Xeryahooda Flavonoid (sida rutin, chlorogenic acid, ferulic acid, iyo caffeic acid) ayaa lagu soo waramayaa inay muujinayaan waxqabadka antioxidants ee caleemaha EU.6].

Inkasta oo ay jireen suugaan ku filan oo ku saabsan sifooyinka phytochemical ee EU, daraasado yar ayaa si kastaba ha ahaatee ka jiray sifooyinka dawooyinka ee xeryahooda kala duwan ee laga soo saaro jilif, miraha, afkoda, iyo caleemaha EU. Warqadan dib u eegista ayaa sifayn doonta macluumaad faahfaahsan oo ku saabsan xeryahooda kala duwan ee laga soo saaray qaybaha kala duwan (jilif, miraha, stem, iyo caleen) ee EU iyo isticmaalka mustaqbalka ee xeryahooda ee guryaha kor u qaadaya caafimaadka oo leh khadadka sayniska ee caddaynta sidaas darteedna waxay bixiyaan agab tixraac. ee codsiga Midowga Yurub.

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Awooda wax bixinta:10000 Qeybaha/Qeybaha bishii

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Lignans iyo asalkoodu waa qaybaha muhiimka ah ee EU.7]. Ilaa hadda, 28 lignans (sida bisepoxylignans, monoepoxylignans, neolignans, iyo sesquilignans) ayaa laga soocay jilif, caleemo, iyo miraha Midowga Yurub. Iridoid glycoside, fasalka dheef-shiid kiimikaad sare, waa qaybta labaad ee ugu weyn ee EU. Iridoids waxaa sida caadiga ah laga helaa dhirta loo yaqaan glycosides. Afar iyo labaatan iridoids ayaa laga soocay oo laga aqoonsaday EU (Shaxda 1). Xeryahooda go'doonsan waxaa ka mid ah geniposidic acid, aucubin, iyo asperuloside kuwaas oo la sheegay in ay leeyihiin sifooyin farmaajo oo ballaaran.8-10]. Laba xeryood oo cusub oo iridoids ah, Eucommides-A iyo -C, ayaa dhowaan la go'doomiyey. Labadan xeryood ee dabiiciga ah waxaa loo tixgeliyaa inay yihiin isku-xidhka iridoid iyo amino acids. Si kastaba ha ahaatee, habka ka dambeeya hawlahooda lama heli karo [11].

2.2. Iskudhisyada Phenolic

Iskudhisyada phenolic ee laga helo cuntooyinka ayaa lagu soo waramayaa inay saameyn togan ku leeyihiin caafimaadka aadanaha.12,13]. Qiyaastii 29 xeryahooda phenolic ayaa la go'doomiyay oo laga aqoonsaday EU.14]. Wadarta guud ee ka kooban xeryahooda phenolic (oo ku jira gallic acid oo u dhiganta dhammaan waxyaabaha laga soosaaray) ayaa lagu falanqeeyay iyadoo la isticmaalayo Folin-Ciocalteu phenol reagent. Saamaynta kala duwanaanshaha xilliyeed ee waxa ku jira xeryahooda qaar iyo antioxidants ayaa la soo sheegay. Isla sanadkaas gudihiisa, wax ka badan phenolics iyo flavonoids ayaa laga helay caleemaha EU bilihii Agoosto iyo May, siday u kala horreeyaan. Rutin, quercetin, geniposidic acid, iyo aucubin ayaa jiray feejignaan sare bilihii May ama June.15]. Waxaa intaa dheer, dhaqdhaqaaqa sare ee 1,1-diphenyl-2-picrylhydrazyl (DPPH) dhaqdhaqaaqa xagjirka ah ee xoqidda iyo awoodda chelating birta ah ayaa laga helay caleemaha EU-da ee la goostay Agoosto. Mawduuca kordhay ee antioxidants-ka cuntada ayaa sidoo kale la soo sheegay bishii Maajo marka la barbar dhigo xilliyada kale ee sanadka.15]. Caleenta EU-da ayaa la ogaaday inay hodan ku tahay aminoacids, fiitamiinnada, macdanta, iyo flavonoids sida quercetin, rutin, iyo geniposidic acid.11,16]. Wadarta 7 flavonoids ayaa laga soocayEucommiadhirta [17]. Rutin iyo quercetin waa flavonoids ugu muhiimsan.18]. Flavonoids waa xeryahooda muhiimka ah kuwaas oo ku badan dabeecadda waxaana loo tixgaliyaa inay yihiin dheef-shiid kiimikaad sare waxayna u shaqeeyaan sida farriimaha kiimikaad, nidaamiyayaal jireed, iyo horjoogayaasha wareegga unugyada.

2.3. Steroids iyo Terpenoids

Lix steroids iyo shan terpenoids ayaa laga soo saaray oo laga soocay EU. Kuwaas waxaa ka mid ahβ-sitosterol, daucosterol, ulmoprenol, betalin, betulic acid, ursolic acid, eucommidiol, rehmaglutin C, iyo 1,4α,5,7α-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester kaas oo si gaar ah uga go'ay jilif EU.19]. Loliolide sidoo kale waa laga soocay caleemaha [20].

2.4. Polysaccharides

Polysaccharides oo ka socda EU muddo 15 maalmood ah oo ka kooban 300-600 mg / kg ayaa lagu soo warramey inay muujinayaan saameyn difaac ah oo kelyaha ah sida lagu arkay malonaldehyde iyo glutathione heerarka ka dib qallafsanaanta kelyaha.21]. Baaritaanka taariikhiga ah ayaa sidoo kale muujiyay caddaynta sifooyinka antioxidative. Waxyaabaha laga soo saaro jilif EU iyadoo la adeegsanayo 70% ethanol waxay sidoo kale muujisay saameyn ka hortag ah cadmium 125-500 mg / kg.22]. Baaritaanka taariikhiga ah ayaa sidoo kale muujiyay in EU-da marka lagu daroPanax pseudoginsengmiisaanka 25% iyo 50%, siday u kala horreeyaan, lix toddobaad oo ah qiyaasta qiyaasta 35.7-41.6 mg / kg waxay samaysay saameyn difaac iftiin leh oo ku saabsan heerka sifaynta glomerular [8]. Laba polysaccharides oo cusub ayaa laga soocay EU, kuwaas oo ah eucomman A iyo B [23].

2.5. Walxaha kale iyo Kiimikada

Amino acids, microelements, fiitamiinnada, iyo asiidhyada dufanka leh ayaa sidoo kale laga soocay EU.17,21-23]. Sun iyo al. Waxa kale oo la helay xeryahooda cusub sida n-octacosanoic acid, iyo tetracosanoic-2,3-dihydroxypropylester ka EU.24].

Halabuurka aysiidhka dufanka leh ee saliidda laga soo saaray abuurka EU-da waxay muujisay uruurin kala duwan oo ah asiidh dufan ah oo polyunsaturated ah sida linoleic acid, linolenic acid (56.51% wadarta dufanka dufanka leh, TFAs), iyo linolelaidic acid (12.66% TFAs). Dhanka kale, aashitada dufanka leh ee monounsaturated ee ugu weyn ee laga soocay abuurka ayaa la ogaaday inay tahay isoleic acid (15.80% TFAs). Asiidhada dufanka badan ee go'doonsan waxaa ka mid ah palmitic acid iyo stearic acid kuwaas oo ka dhigan 9.82% iyo 2.59% TFAs, siday u kala horreeyaan.